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Procedural Sedation

Procedural sedation is medicine to ease discomfort, pain, and anxiety during a procedure. The medicine is often given through an IV (intravenous) line in your arm or hand. In some cases, the medicine may be taken by mouth or inhaled. While you are under sedation, you will likely be awake. But you may not remember anything afterward.

Why procedural sedation is used

Sedation is used for many types of procedures. The goal is to reduce pain, anxiety, and stressful memories of a procedure. It can help your healthcare provider treat you. For example, having a broken bone fixed may be easier if you feel relaxed.

This type of sedation is used only for short, basic procedures. It's not used for complex surgery. Some procedures that use this type of sedation include:

  • Dental surgery

  • Breast biopsy, to take a sample of breast tissue

  • Endoscopy, to look at gastrointestinal problems

  • Bronchoscopy, to check for lung problems

  • Bone or joint realignment, to fix a broken bone or dislocated joint

  • Minor foot or skin surgery

  • Electrical cardioversion, to restore a normal heart rhythm

  • Lumbar puncture, to assess neurological disease

Risks of procedural sedation

Risks and possible side effects include:

  • Headache

  • Nausea and vomiting

  • Unpleasant memory of the procedure

  • Lowered rate of breathing

  • Changes in heart rate and blood pressure (rare)

  • Inhalation of stomach contents into your lungs (rare)

Side effects will likely go away shortly after the procedure. Your healthcare team will watch your heart rate and breathing during and after your sedation. This is to help prevent problems.

Your own risks may vary. They can be based on your age and your overall health. They also depend on the type of sedation you are given. Talk with your healthcare provider about the risks that apply most to you.

Getting ready for procedural sedation

Talk with your healthcare provider about how to get ready for your procedure. Tell them about all the medicines you take. This includes over-the-counter medicines, such as ibuprofen. It also includes vitamins, herbs, and other supplements. You may need to stop taking some medicines before the procedure, such as blood thinners and aspirin. If you smoke, you should stop. This is to lessen the chance of a lung problem. Talk with your healthcare provider if you need help to stop smoking.

Tell your healthcare provider if you:

  • Have had any problems in the past with sedation or anesthesia

  • Have had any recent changes in your health, such as an infection or fever

  • Are pregnant or think you could be


  • Ask a family member or friend to take you home after the procedure. You can’t drive on the day you have sedation.

  • Follow any directions you are given for not eating or drinking before procedure.

  • Don't make any important decisions, such as financial or legal, on the day after you have sedation.

  • Follow all other instructions from your healthcare provider.

During your procedural sedation

You may have your procedure in a hospital or a medical clinic. Sedation is done by a trained healthcare provider. In general, you can expect the following:

  • You will be given medicine through an IV line in your arm or hand. Or you may receive a shot. The medicine may also be given by mouth. Or you may inhale it through a mask.

  • If you have medicine through an IV, you may feel the effects very quickly. You will start to feel relaxed and drowsy.

  • During the procedure, your heart rate, breathing, and blood pressure will be closely watched. Your breathing and blood pressure may decrease a little. But you will likely not need help with your breathing. You may receive a little extra oxygen. This is done through a mask or some soft plastic prongs under your nose.

  • You will probably be awake the entire time. If you do fall asleep, you should be easy to wake up, if needed. You should feel little or no pain.

  • When your procedure is over, the sedative medicine will be stopped.

After your procedural sedation

You will begin to feel more awake and aware. But you will likely be drowsy for a while afterward. You will be closely watched as you become more alert. You may have a faint memory of the procedure. Or you may not remember it at all.

You should be able to return home within 1 to 2 hours after your procedure. Plan to have someone stay with you for a few hours. Side effects, such as headache and nausea, may go away quickly. Tell your healthcare provider if they continue.

Don’t drive or make any important decisions for at least 24 hours. Be sure to follow all after-care directions.

When to call your healthcare provider

Have someone call your healthcare provider right away if any of the following occur:

  • Drowsiness that gets worse

  • Weakness or dizziness that gets worse

  • Repeated vomiting

  • Severe or ongoing pain from the procedure, not relieved by the pain medicine

  • Fever of 100.4º F (38°C) or higher, or as directed by your healthcare provider

  • New rash

Call 911

Have someone call 911 if any of the following occur:

  • Shortness of breath

  • Chest pain

  • Loss of consciousness or you can't be awakened

Online Medical Reviewer: Jimmy Moe MD
Online Medical Reviewer: Raymond Turley Jr PA-C
Online Medical Reviewer: Tara Novick BSN MSN
Date Last Reviewed: 7/1/2022
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